lnc’edin to Myelin
نویسندگان
چکیده
منابع مشابه
lnc’edin to Myelin
Long non-coding RNAs (lncRNAs) have been implicated in numerous developmental processes. In a technical and bioinformatics tour-de-force, He et al. (2017) provide critical insight into the dynamics of lncRNA expression, function, and mechanism during oligodendrocyte development and after injury.
متن کاملEpigenetic Approaches to Myelin Biology
understanding of the molecular mechanisms by which genes and environment interact. This new field of biology, epigenetics, describes the intricate and highly complex processes by which the 20,000 or so genes in our bodies are controlled throughout the life cycle. During development, the selective turning on or off of collections of genes govern the differentiation of stem cells into organs, and...
متن کاملAxon degeneration: Linking axonal bioenergetics to myelin
The mechanisms by which axonal degeneration occurs, even in the presence of apparently normal myelin sheaths, remain unknown. In this issue, Yin et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201607099) study mutant mice in which proteolipid protein is replaced by the peripheral myelin protein P0 and describe a number of early axonal abnormalities, which together suggest that aberrant ...
متن کاملCan oligodendrocytes attached to myelin proliferate?
The uptake of thymidine by oligodendrocytes in the brains of adult mice was examined after the induction of cortical traumatic lesions in an attempt to determine whether mature oligodendrocytes actively attached to myelin sheaths were capable of proliferating. In view of the great difficulty in visualizing the connection between a given oligodendrocyte and a myelin sheath even in the normal adu...
متن کاملMyelin movement
alcium just got a promotion. Findings by Caroppo et al. (page 111) reveal that in addition to its many roles inside the cell, Ca 2 ϩ has a distinct extracellular purpose: it acts via a Ca 2 ϩ receptor (CaR) to regulate the function of gastric epithelial cells. It has been known for some time that extracellular Ca 2 ϩ can be sensed by the CaR. The team noted that a Ca 2 ϩ gradient was generated ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuron
سال: 2017
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2017.01.002